Cam Newton - QB - Carolina Panthers
Carolina Panthers QB Cam Newton (foot) suffered a foot injury during the preseason game Thursday, Aug. 22, and will not return.
Huddle Up: Fantasy players should monitor the situation to determine the severity of Newton's injury. He is a risky option because of his injury history but can be a low-end No. 1 fantasy quarterback if healthy.
Aaron Rodgers - QB - Green Bay Packers
Green Bay Packers QB Aaron Rodgers, RB Aaron Jones and WR Davante Adams are among the 33 players that will not play in the preseason game Thursday, Aug. 22.
Huddle Up: Rodgers, Jones and Adams likely will not play in a game again until Week 1. All three players will be weekly starting options in all fantasy leagues with Rodgers and Adams being one of the first players selected from their position.
A.J. Brown - WR - Tennessee Titans
Tennessee Titans WR A.J. Brown is expected to play in the preseason game Sunday, Aug. 25. Brown said he is still working on his conditioning.
Huddle Up: Brown missed a majority of training camp because of an injury but is still on track to becoming a solid part of the team's passing game. He can be a late-round option in fantasy leagues as depth at the position.
Will Fuller - WR - Houston Texans
Houston Texans WR Will Fuller (knee) left practice early Thursday, Aug. 22, but head coach Bill O'Brien said Fuller is not hurt and that the team is managing his snaps during practice.
Huddle Up: Fuller is coming back from a torn anterior cruciate ligament but is on track to play Week 1. He has shown a good chemistry with Deshaun Watson in the past and can be a No. 3 receiver in fantasy leagues.
Nick Foles - QB - Jacksonville Jaguars
Jacksonville Jaguars QB Nick Foles has reportedly 'shown good chemistry' with WRs Dede Westbrook, Chris Conley and DJ Chark Jr. in practice, according to the team's website.
Huddle Up: Fantasy owners should get a peek at the chemistry when they the Jaguars square off with the Miami Dolphins on Thursday night. Jacksonville may be an underrated source of passing-game production this season, as new offensive coordinator John DeFilippo has shown a heavy tendency to lean on the aerial attack. Westbrook figures to be the only receiver worth starting in fantasy right away, however, presumably as a low-end WR3 or flex option.
Amari Cooper - WR - Dallas Cowboys
Updating previous reports, Dallas Cowboys WR Amari Cooper (foot) is dealing with an intrinsic muscle strain in his foot as opposed to plantar fasciitis, according to Mickey Spagnola of the team's website.
Huddle Up: The foot's intrinsic muscles stabilize the foot much like the core muscles in a person's spine stabilizes and protects the spine. Neither the team nor Cooper seem overly concerned about the injury, so fantasy owners can probably breathe easy ... for now. Nevertheless, expect Cooper to get rest days and be a regular on the injury report this season.
Keke Coutee - WR - Houston Texans
Houston Texans WR Keke Coutee (ankle) remains sidelined with a sprained ankle, according to Aaron Wilson of the Houston Chronicle.
Huddle Up: This will play nicely into the narrative that Coutee is injury-prone and/or a slow healer. For what it's worth, NFL Network's Ian Rapoport suggested the injury was "not major" at the time it happened, so it's probably best for owners to wait for another update before getting too concerned. Duke Johnson would likely benefit the most if Coutee is forced to miss regular-season action, while DeAndre Carter would likely step into Coutee's slot role and be worthy of a bench spot in deeper leagues.
Ezekiel Elliott - RB - Dallas Cowboys
Dallas Cowboys RB Ezekiel Elliott reportedly received a contract extension offer from the team that would make him one of the two highest-paid running backs in the league, according to a source.
Huddle Up: This would suggest the offer was somewhere between Le'Veon Bell's four-year deal worth $52.5 million and Todd Gurley's four-year pact worth $57.5 million. The fact he hasn't already signed the offer is a pretty good indication he wants more than Gurley. There has been much optimism that Elliott's deal will get done before the start of the regular season, but the clock is ticking. Owners need to start preparing for the possibility he could miss - or be limited at the very least - for the first couple weeks of the season.
Ben Roethlisberger - QB - Pittsburgh Steelers
Pittsburgh Steelers QB Ben Roethlisberger said Thursday, Aug. 22, that he's 'pretty sure' he'll play Sunday, Aug. 25, in the team's preseason game against the Tennessee Titans.
Huddle Up: Big Ben is coming off a huge 2018 season but has since lost longtime top target Antonio Brown. Value him as a high-end QB2.
Anthony Miller - WR - Chicago Bears
Chicago Bears WR Anthony Miller (ankle) could have a limited role in the offense early in the season as he missed most of organized team activities and minicamp to a shoulder injury and most of the preseason with an ankle injury.
Huddle Up: Miller is still someone to target late in drafts for his long-term value, but he has struggled to learn the nuances of the offense and now has missed most of the offseason and preseason. He might be someone to keep an eye on via the waiver wire for the first couple of weeks.
Michael Crabtree - WR - Free Agent
The Arizona Cardinals signed free-agent WR Michael Crabtree (Ravens) to a one-year contract on Wednesday, Aug. 21.
Huddle Up: The two sides failed to come to terms earlier this month, but after Hakeem Butler broke his hand and Kevin White was released the Cardinals decided to revisit bringing the veteran on board to help stabilize a position that's long on potential but short on experience. At this stage of his career, Crabtree is a steady underneath option and potential red-zone target (he scored 25 TDs with the Raiders in 2015-17), but he's nothing more than a watch list candidate for the time being.
Nick Chubb - RB - Cleveland Browns
Cleveland Browns RB Nick Chubb is expected to see more work catching the football in 2019. 'I think he's going to be special like he was last year,' running backs coach Stump Mitchell said Wednesday, Aug. 21. 'He'll be used a little more in the passing game than he was last year. Nick just continues to improve on the skillset that he has, and I think he has a fantastic skillset.'
Huddle Up: Chubb will be a tremendous RB1 in most fantasy formats, and a bump in catches and receiving yards would boost his value in PPR formats significantly, at least until Kareem Hunt is ready to return midseason from his suspension.
Alexander Mattison - RB - Minnesota Vikings
Minnesota Vikings RB Alexander Mattison has been the talk of training camp and the preseason, according to national writer Jay Glazer. 'I mean, to a man, couldn't stop preaching his gospel,' Glazer said of the Vikings.
Huddle Up: Mattison has been coming into the preseason games ahead of Mike Boone, who has also been pretty strong in his play. Right now Dalvin Cook is the obvious starter, but if you're looking for a handcuff, look to Mattison in the later rounds. Even if you don't own stock in Cook, Mattison is also worth adding for running back depth in the later rounds, as it might take one Cook injury to thrust the rookie into the spotlight.
DK Metcalf - WR - Seattle Seahawks
Seattle Seahawks WR D.K. Metcalf (knee) is considered week-to-week because his knee surgery showed minimal damage, according to head coach Pete Carroll. Carroll is not able to say if Metcalf will be ready for Week 1 but indicated that Metcalf should not be sidelined long.
Huddle Up: Metcalf has played well at times during the preseason but likely will be eased back into the lineup once he is cleared to play. Fantasy players could consider Metcalf as a late-round option that could be used against favorable matchups.
Antonio Brown - WR - Oakland Raiders
Oakland Raiders WR Antonio Brown is traveling with the team to Winnipeg for their preseason game Thursday, Aug. 22. QB Derek Carr said he plans to work with Brown during pregame warmups.
Huddle Up: Brown is still dealing with the helmet issue but has been with the team this week and will be able to build some chemistry with Carr. Brown is a No. 1 fantasy receiver as long as he does not miss any time in the regular season.
Melvin Gordon - RB - Los Angeles Chargers
Los Angeles Chargers RB Melvin Gordon is expected to continue his holdout through the start of the regular season since there has not been any progress made in contract talks, according to sources.
Huddle Up: Gordon's fantasy value will take a big hit if he decides to sit out regular season games and will drop on draft boards. Austin Ekeler and Justin Jackson will handle the carries while Gordon holds out, and both players had success last season. Ekeler can be considered a No. 2 or No. 3 fantasy back, while Jackson could be a possible handcuff or late-round option.
Frank Gore - RB - Buffalo Bills
Buffalo Bills RBs LeSean McCoy and Frank Gore will both see more playing time during the third preseason game Friday, Aug. 23.
Huddle Up: McCoy probably will keep the starting job this season, but Gore should also have a solid role in the running game. McCoy probably can be a No. 3 running back, while Gore could be a handcuff to McCoy or a No. 4 or No. 5 back on a fantasy roster.
Dawson Knox - TE - Buffalo Bills
Buffalo Bills TE Dawson Knox (hamstring) will be available to play in the preseason game Friday, Aug. 23, but head coach Sean McDermott said he is not sure if Knox will be on a snap count.
Huddle Up: Knox recently returned to practice, but the team may ease him back into playing time. He has a decent chance to open the season as the starting tight end with Tyler Kroft still dealing with an injury. Fantasy players probably should avoid him even if he is named the starter.
Rashaad Penny - RB - Seattle Seahawks
Seattle Seahawks RB Rashaad Penny has 13 yards on 12 carries in two preseason games, and he has fallen further behind RB Chris Carson, in the opinion of NBC Sports Northwest's Joe Fann. Head coach Pete Carroll backed Penny by saying: 'We've got to block for him better. He didn't have a chance.'
Huddle Up: Penny will need a strong second half of the preseason to be worth more than RB5 or handcuff at this point. Carson looks like a solid RB2.
Mike Evans - WR - Tampa Bay Buccaneers
Tampa Bay Buccaneers WR Mike Evans (leg) won't play in the third preseason game Friday, Aug. 23.
Huddle Up: Evans' injury isn't believed to be serious and shouldn't affect his Week 1 status. He's a WR1, but he has dealt with lingering issues like this throughout his career.