Sunday updates will begin when teams start releasing official pregame inactives and starter information to the league. This is typically around 60-90 minutes prior to the kickoff of their game.
Week 1 gameday inactives, weather and notes
Key game-time decisions
Early games: WR Emmanuel Sanders (active)
Afternoon games: WR Odell Beckham Jr. (INACTIVE)
Sunday night: None
Monday night: None
Sunday early games
Philadelphia Eagles at Atlanta Falcons (1:00 p.m. EDT)
Kickoff Weather: Dome stadium
Eagles
Inactives: LB Davion Taylor, S Rodney McLeod, OL Landon Dickerson, CB Mac McCain and QB Gardner Minshew
Lineup notes: No noteworthy injuries for fantasy
Falcons
Inactives: CB Darren Hall, DT Ta’Quon Graham, RB Wayne Gallman, QB Feleipe Franks and WR Frank Darby
Lineup notes: No noteworthy injuries for fantasy
Pittsburgh Steelers at Buffalo Bills (1:00 p.m. EDT)
Kickoff Weather: 73 degrees, overcast
Steelers
Inactives: CB Ahkello Witherspoon, DE Isaiahh Loudermilk, QB Dwayne Haskins, OG Rashaad Coward and LB Robert Spillane
Lineup notes: No noteworthy injuries for fantasy
Bills
Inactives: LB Andre X. Smith, OT Tommy Doyle, DE Carlos Basham Jr., RB Zack Moss and DL Star Lotulelei
Lineup notes: WR Emmanuel Sanders (foot) is questionable and was limited all week. He is likely a game-time decision. RB Zack Moss is a healthy scratch.
Minnesota Vikings at Cincinnati Bengals (1:00 p.m. EDT)
Kickoff Weather: 81 degrees, partly cloudy
Vikings
Inactives: OT Christian Darrisaw, LB Anthony Barr, TE Ben Ellefson, LB Blake Lynch, QB Kellen Mond, CB Cameron Dantzler and DE Patrick Jones II
Lineup notes: No noteworthy injuries for fantasy
Bengals
Inactives: CB Trae Waynes, CB Nick McCloud, OG Fred Johnson, DT Tyler Shelvin and OT D’Ante Smith
Lineup notes: No noteworthy injuries for fantasy
San Francisco 49ers at Detroit Lions (1:00 p.m. EDT)
Kickoff Weather: Dome stadium
49ers
Inactives: OG Aaron Banks, DT Javon Kinlaw, CB Emmanuel Moseley, CB Josh Norman and RB Trey Sermon
Lineup notes: WR Brandon Aiyuk (hamstring) was a full participant all week and is not on the injury report. Backup QB Trey Lance (finger) was limited all week but didn’t receive a designation. RB Trey Sermon is a surprise healthy scratch.
Lions
Inactives: WR KhaDarel Hodge, DT Levi Onwuzurike, WR Tom Kennedy, OG Tommy Kraemer, RB Jermar Jefferson and LB Julian Okwara
Lineup notes: TE T.J. Hockenson (shoulder) participated every day in full and is not on the injury report. Starting LT Taylor Decker (finger) was placed on Injured Reserve. Gameday media reports say RB Jamaal Williams will carry the load, even with RB D’Andre Swift not being on the injury report this week.
Arizona Cardinals at Tennessee Titans (1:00 p.m. EDT)
Kickoff Weather: 83 degrees, clear
Cardinals
Inactives: CB Luq Barcoo, CB Tay Gowan, RB Eno Benjamin, OT Joshua Miles and QB Chris Streveler
Lineup notes: No noteworthy injuries for fantasy
Titans
Inactives: WR Cameron Batson, S Chris Jackson, DE Rashad Weaver, TE Tommy Hudson, LB David Long Jr., WR Josh Reynolds and OT Dillon Radunz
Lineup notes: WR Josh Reynolds (foot) was limited Thursday and Friday, and he will not play through a questionable tag.
Seattle Seahawks at Indianapolis Colts (1:00 p.m. EDT)
Kickoff Weather: 81 degrees, clear (retractable-roof dome)
SEahawks
Inactives: DL L.J. Collier, OT Stone Forsythe, QB Jake Luton, RB Alex Collins, OT Dakoda Shepley and CB Blessuan Austin
Lineup notes: RB Chris Carson (neck) appeared on the participation list as a full-go Friday. He is not on the injury report. WR DK Metcalf (calf) was listed as limited Friday but didn’t get an injury designation. Both will play.
Colts
Inactives: OT Eric Fisher, DL Isaac Rochell, DE Kemoko Turay, CB Chris Wilcox, OG Danny Pinter, OG Will Fries and CB Xavier Rhodes
Lineup notes: QB Carson Wentz (foot) fully practiced all week and is not on the injury report. Starting LT Eric Fisher (Achilles) has been ruled out, and star OG Quenton Nelson (back, foot) is questionable but will play.
Los Angeles Chargers at Washington Football Team (1:00 p.m. EDT)
Kickoff Weather: 82 degrees, clear
Chargers
Inactives: LB Amen Ogbongbemiga, QB Easton Stick, RB Joshua Kelley, TE Tre’ McKitty and DB Trey Marshall
Lineup notes: RB Austin Ekeler (hamstring) didn’t go Wednesdays or Thursday but was limited Friday, drawing a questionable tag. Reports say he will see a full workload.
Football team
Inactives: DE Shaka Toney, QB Kyle Allen, CB Darryl Roberts, OT Saahdiq Charles and TE Sammis Reyes
Lineup notes: WR Curtis Samuel (groin) was placed on the Reserve/Injured list and will miss at least three games.
New York Jets at Carolina Panthers (1:00 p.m. EDT)
Kickoff Weather: 82 degrees, clear
Jets
Inactives: RB La’Mical Perine, CB Jason Pinnock, DT Jonathan Marshall, RB Josh Adams, LB Quincy Williams and WR Keelan Cole
Lineup notes: WR Jamison Crowder (illness) will not be activated from the Reserve/COVID-19 list prior to kickoff.
Panthers
Inactives: OT Mike Jordan, WR Shi Smith, DE Darryl X. Johnson, OG Deonte Brown, DT Phil Hoskins and LB Clay Johnston
Lineup notes: No noteworthy injuries for fantasy
Jacksonville Jaguars at Houston Texans (1:00 p.m. EDT)
Kickoff Weather: 85 degrees, humid, mostly cloudy (retractable-roof dome)
Jaguars
Inactives: DT Jay Tufele, DL Adam Gotsis, S Daniel Thomas, DE Jordan Smith, CB Tre Herndon, OT Walker Little and TE Jacob Hollister
Lineup notes: WRs DJ Chark Jr. (finger) and Marvin Jones Jr. (shoulder) both avoided the injury report and will play.
Texans
Inactives: RB Scottie Phillips, CB Lonnie Johnson, WR Anthony Miller, LB Jonathan Greenard, QB Deshaun Watson, TE Brevin Jordan, LB Kevin Pierre-Louis and CB Jimmy Moreland
Lineup notes: WR Anthony Miller is a healthy scratch. QB Deshaun Watson, as expected, will not play. QB Tyrod Taylor will start.
Sunday afternoon games
Cleveland Browns at Kansas City Chiefs (4:25 p.m. EDT)
Kickoff Weather: 90 degrees, clear
Browns
Inactives: OT James Hudson, OL Michael Dunn, DT Tommy Togiai, LB Tony Fields II, S Grant Delpit, PK Chris Naggar and WR Odell Beckham Jr.
Lineup notes: WR Odell Beckham Jr. (knee) is questionable and was limited all week. He has been ruled out in a somewhat surprising move.
Chiefs
Inactives: DE Frank Clark, C Austin Blythe, WR Daurice Fountain, CB DeAndre Baker, S Tyrann Mathieu and OT Laurent Duvernay-Tardif
Lineup notes: WR Mecole Hardman (oblique) was a full participant Thursday and Friday after being limited Wednesday. He is not on the injury report.
Miami Dolphins at New England Patriots (4:25 p.m. EDT)
Kickoff Weather: 80 degrees, partly cloudy
Dolphins
Inactives: WR Preston Williams, DB Elijah Campbell, CB Trill Williams, OT Greg Little and CB Noah Igbinoghene
Lineup notes: WR Preston Williams (foot) couldn’t overcome a questionable tag after being limited all week in practice.
Patriots
Inactives: LB Ronnie Perkins, CB Shaun Wade, TE Devin Asiasi, OT Yodny Cajuste, RB J.J. Taylor and PK Quinn Nordin
Lineup notes: WR Nelson Agholor (ankle) is questionable after going limited, out, and limited, respectively, in practice Wednesday through Friday. He will play. PK Nick Folk is the gameday kicker.
Green Bay Packers at New Orleans Saints* (4:25 p.m. EDT)
*played in Jacksonville, due to Hurricane Ida
Kickoff Weather: 86 degrees, partly cloudy
Packers
Inactives: LB Isaiah McDuffie, DT Jack Heflin, CB Shemar Jean-Charles, C Jake Hanson and S Vernon Scott
Lineup notes: No noteworthy injuries for fantasy
Saints
Inactives: DL Payton Turner, FB Adam Prentice, CB Jordan Miller, LB Chase Hansen and QB Ian Book
Lineup notes: TE Adam Trautman (foot) missed a few weeks but is not on the injury report for the season-opening week. WR Tre’Quan Smith (hamstring) has been ruled out.
Denver Broncos at New York Giants (4:25 p.m. EDT)
Kickoff Weather: 85 degrees, partly cloudy
Broncos
Inactives: OT Cameron Fleming, S Jamar Johnson, DT McTelvin Agim, TE Andrew Beck, LB Bradley Chubb, RB Nate McCrary and CB Kary Vincent Jr.
Lineup notes: TE Noah Fant (knee) was a full-go Thursday and Friday week and is will play after avoiding the injury report.
Giants
Inactives: TE Evan Engram, CB Sam Beal, CB Josh Jackson, LB Justin Hilliard, DE Quincy Roche and WR Collin Johnson
Lineup notes: RB Saquon Barkley (knee) is questionable after being limited all week. He will play but on a snap count. TE Evan Engram (calf) has been ruled out, and WR Kenny Golladay (hamstring) is not on the injury report after being limited all week.
Sunday Night Football
Chicago Bears at Los Angeles Rams (8:20 p.m. EDT)
Kickoff Weather: 74 degrees, clear (open-air dome)
Bears
Inactives: QB Nick Foles, WR Breshad Perriman, CB Duke Shelley, LB Joel Iyiegbuniwe, OL Lachavious Simmons, TE Jesper Horsted, DT Eddie Goldman
Lineup notes: WR Darnell Mooney (back) is questionable but will play after fully practicing Friday.
Rams
Inactives: QB Bryce Perkins, DB JuJu Hughes, DB JR Reid, OL Alaric Jackson, WR Ben Skowronek, DL Bobby Brown
Lineup notes: No noteworthy injuries for fantasy
Monday Night Football
Baltimore Ravens at Las Vegas Raiders (8:15 p.m. EDT)
Kickoff Weather: Dome stadium
Ravens
Lineup notes: RB Gus Edwards (knee) was lost for the year after suffering a torn ACL. RB Ty’Son Williams and newcomer Latavius Murray figure to share touches in a manner favoring the former.
Raiders
Lineup notes: RB Josh Jacobs (toe) was limited in practice Thursday and Friday. He could see a lighter workload Monday night, but Jacobs is not on the injury report after being limited as a precaution in Saturday’s practice.
All weather reports are courtesy of The Football Database.
