Sunday updates will begin when teams start releasing official pregame inactives and starter information to the league. This is typically around 60-90 minutes prior to the kickoff of their game.
Weather forecasts are courtesy of The Football Database.
Week 5 gameday inactives, weather and notes
TODAY’S KEY GAME-TIME DECISIONS
Early games: RB Dalvin Cook (inactive), WR DeVante Parker (inactive), WR Curtis Samuel (active), WR Courtland Sutton (active), RB Melvin Gordon (active), RB Joe Mixon (active), RB Jamaal Williams (active), TE T.J. Hockenson (active), RB Antonio Gibson (active)
Afternoon games: WR Amari Cooper (active), RB Ezekiel Elliott (active), RB Chase Edmonds (active)
New York Jets at Atlanta Falcons in London (9:30 a.m. EST)
Kickoff Weather: 64 degrees, 40 percent chance of scattered showers
Inactives: S Adrian Colbert, S Marcus Maye, WR Jeff Smith, DT Jonathan Marshall, TE Tyler Kroft, RB La’Mical Perine and DB Isaiah Dunn
Lineup notes: OT Mekhi Becton (knee) will miss several more weeks after knee surgery. WR Elijah Moore (concussion) and WR Denzel Mims (illness) practiced Friday and are off the report. Both are active.
Inactives: WR Russell Gage Jr., CB Avery Williams, WR Calvin Ridley, DE Marlon Davidson, S Erik Harris, DL John Cominsky and QB Feleipe Franks
Lineup notes: WR Calvin Ridley (personal) has been ruled out. WR Russell Gage (ankle) is out again with an ankle injury.
Green Bay Packers at Cincinnati Bengals (1:00 p.m. EST)
Kickoff Weather: 79 degrees, mostly cloudy
Inactives: DT Jack Heflin, LB Jaylon Smith, C Josh Myers, C Elgton Jenkins, S Vernon Scott and CB Rasul Douglas
Lineup notes: WR Marquez Valdes-Scantling (hamstring) landed on IR and will miss a couple of weeks at least. RB Aaron Jones (ankle) was limited all week, but he’s off the injury report. Standout CB Jaire Alexander (shoulder) was placed on IR, and OG/OT Elgton Jenkins (ankle) is questionable. CB Kevin King (concussion) is set to return.
Inactives: WR Mike Thomas, OG Fred Johnson, CB Nick McCloud, DT Tyler Shelvin and DE Darius Hodge
Lineup notes: WR Tee Higgins (shoulder) returns after a full practice Friday. RB Joe Mixon (ankle) was out of practice Friday, and the team worked him out Saturday. He will play, but RBs Samaje Perine and Chris Evans could see larger roles.
Detroit Lions at Minnesota Vikings (1:00 p.m. EST)
Kickoff Weather: Dome stadium
Inactives: CB Daryl Worley, DL Jashon Cornell, DT Eric Banks, RB Jermar Jefferson, WR Tom Kennedy and DE Jessie Lemonier
Lineup notes: WR Tyrell Williams (concussion) remains on IR. RB D’Andre Swift (groin) TE T.J. Hockenson (knee) and RB Jamaal Williams (hip) were questionable, but all three will play.
Inactives: DE Patrick Jones II, WR Ihmir Smith-Marsette, RB Dalvin Cook, DL Michael Pierce, QB Kellen Mond and OG Wyatt Davis
Lineup notes: RB Dalvin Cook (ankle) returned to practice in a limited fashion Friday, but he wasn’t able to get right in time. RB Alexander Mattison gets the start.
Denver Broncos at Pittsburgh Steelers (1:00 p.m. EST)
Kickoff Weather: 69 degrees, partly cloudy
Inactives: OT Cameron Fleming, S Jamar Johnson, DT McTelvin Agim, CB Ronald Darby, CB Kary Vincent Jr. and QB Brett Rypien
Lineup notes: WR Jerry Jeudy (ankle) remains on IR but could return later this month. QB Teddy Bridgewater (concussion) was cleared and will start. WR Courtland Sutton (ankle) and RB Melvin Gordon (lower leg) both will play through questionable designations.
Inactives: CB Ahkello Witherspoon, WR James Washington, LB Buddy Johnson, CB Cameron Sutton and QB Dwayne Haskins
Lineup notes: WR Chase Claypool (hamstring), QB Ben Roethlisberger (pectoral, hip) and WR JuJu Smith-Schuster (ribs) practiced fully Friday and are good to go. WR James Washington (groin) has been ruled out.
Miami Dolphins at Tampa Bay Buccaneers (1:00 p.m. EST)
Kickoff Weather: 83 degrees, clear
Inactives: TE Hunter Long, WR DeVante Parker, CB Trill Williams, DL John Jenkins, CB Noah Igbinoghene and OT Greg Little
Lineup notes: QB Tua Tagovailoa (ribs) and WR Will Fuller (finger) are on IR. WR DeVante Parker (shoulder, hamstring) couldn’t overcome a questionable tag and is inactive.
Inactives: OG Nick Leverett, DE Patrick O’Connor, S Antoine Winfield Jr., RB Ke’Shawn Vaughn, TE Rob Gronkowski, QB Kyle Trask and WR Jaelon Darden
Lineup notes: TE Rob Gronkowski (ribs) has been ruled out for Week 5. RB Giovani Bernard (knee) graduated to a full practice Friday and will play, despite a questionable listing. WR Chris Godwin (thumb) practiced fully Friday and will play. WR Antonio Brown (knee) was out of practice all week but carries no injury tag.
New Orleans Saints at Washington Football Team (1:00 p.m. EST)
Kickoff Weather: 72 degrees, mostly cloudy
Inactives: QB Ian Book, DE Jalyn Holmes, WR Lil’Jordan Humphrey, CB Desmond Trufant, OT Terron Armstead and C Erik McCoy
Lineup notes: WR Michael Thomas (ankle) remains on the PUP and can return in Week 7. LT Terron Armstead (elbow) and C Erik McCoy (calf) are out.
Inactives: WR Dyami Brown, DE Shaka Toney, CB Danny Johnson, TE Jace Sternberger, OG Brandon Scherff and WR Cam Sims
Lineup notes: QB Ryan Fitzpatrick (hip) remains on IR. TE Logan Thomas (hamstring) joined him this week. WR Curtis Samuel (groin) and RB Antonio Gibson (shin) were deemed questionable but are active.
Philadelphia Eagles at Carolina Panthers (1:00 p.m. EST)
Kickoff Weather: 73 degrees, mostly cloudy
Inactives: OG Jack Anderson, OT Lane Johnson, CB Mac McCain, QB Gardner Minshew and DT Marlon Tuipulotu
Lineup notes: OT Lane Johnson (personal) has been ruled out.
Inactives: LB Shaq Thompson, DE Darryl X. Johnson, WR Shi Smith, DT Phil Hoskins, OT Cameron Erving, CB Rashaan Melvin and RB Christian McCaffrey
Lineup notes: RB Christian McCaffrey (hamstring) was limited in practice all week but remains doubtful.
Tennessee Titans at Jacksonville Jaguars (1:00 p.m. EST)
Kickoff Weather: 76 degrees, clear
Inactives: WR Nick Westbrook-Ikhine, RB Mekhi Sargent, P Brett Kern, WR Julio Jones, OG Ty Sambrailo, LB Bud Dupree and DL Woodrow Hamilton
Lineup notes: WR Julio Jones (hamstring) is out once again. On the bright side, WR A.J. Brown (hamstring) returns in Week 5. WR Nick Westbrook-Ikhine (hamstring) was questionable and fully practiced Friday, but he wasn’t able to get right prior to kickoff.
Inactives: DE Jordan Smith, PK Josh Lambo, CB Tyson Campbell, LB Lerentee McCray and DL Roy Robertson-Harris
Lineup notes: WR D.J. Chark Jr. (ankle) was placed on IR and is likely to miss the rest of the year. RB Carlos Hyde (shoulder, tooth) practiced fully all week and is good to go. PK Matthew Wright will handle the kicking duties.
New England Patriots at Houston Texans (1:00 p.m. EST)
Kickoff Weather: 84 degrees, humid, mostly cloudy (retractable-roof dome)
Inactives: LB Ronnie Perkins, OG Shaq Mason, CB Shaun Wade, S Jalen Mills, TE Devin Asiasi and RB J.J. Taylor
Lineup notes: PK Nick Folk (knee) was limited all week and is questionable but will kick. New England will be left with C David Andrews as the lone Week 1 starter along the offensive line who is available for this contest. LT Isaiah Wynn and LG Michael Onwenu couldn’t clear the COVID-19 protocol, RG Shaq Mason (abdomen) was ruled out Friday, and RT Trent Brown (calf) was placed on IR Saturday.
Inactives: RB Scottie Phillips, CB Jimmy Moreland, TE Brevin Jordan, QB Deshaun Watson, DL Charles Omenihu, RB Rex Burkhead and WR Danny Amendola
Lineup notes: QB Tyrod Taylor (hamstring) remains on IR for the foreseeable future. RB Rex Burkhead (hip) has been ruled out. WR Danny Amendola (thigh) is inactive after being limited all week.
Chicago Bears at Las Vegas Raiders (4:05 p.m. EST)
Kickoff Weather: Dome stadium
Inactives: DL Akiem Hicks, TE J.P. Holtz, QB Nick Foles, TE Jesse James, WR Breshad Perriman and LB Joel Iyiegbuniwe
Lineup notes: RB David Montgomery (knee) has been placed on IR. RB Damien Williams (quadriceps) practiced all week and will fill in as the lead back. WR Darnell Mooney (groin) practiced fully as well and is good to go. Rookie QB Justin Fields was named the starter for the remainder of the season.
Inactives: DE Malcolm Koonce, DL Damion Square, RB Peyton Barber and OT Jackson Barton
Lineup notes: RB Josh Jacobs (ankle), WR Hunter Renfrow (ankle) and TE Darren Waller (knee) all practiced Friday and are off the injury report. RB Peyton Barber (toe) will take a seat.
Cleveland Browns at Los Angeles Chargers (4:05 p.m. EST)
Kickoff Weather: 76 degrees, clear (open-air dome)
Inactives: S Richard LeCounte III, DE Jadeveon Clowney, OT Jedrick Wills, DT Tommy Togiai, LB Tony Fields II, OG Chris Hubbard and CB Greg Newsome
Lineup notes: WR Jarvis Landry (knee) remains on IR. WR Odell Beckham Jr. (shoulder) practiced Friday and is good to go. TE David Njoku (knee) and DE Myles Garrett (knee, ankle) will play in Week 5. Starting LT Jedrick Wills (ankle) will miss Week 5.
Inactives: QB Easton Stick, RB Justin Jackson, TE Tre’ McKitty, OT Brenden Jaimes and DB Trey Marshall
Lineup notes: WR Keenan Allen (ankle), RB Austin Ekeler (ankle) and S Derwin James (toe, shoulder) practiced fully Friday and don’t have injury designations. RB Justin Jackson (groin) sees his doubtful tag become an inactive one.
New York Giants at Dallas Cowboys (4:25 p.m. EST)
Kickoff Weather: 86 degrees, partly cloudy (retractable-roof dome)
Inactives: CB Sam Beal, SS Jabrill Peppers, OG Ben Bredeson, WR Sterling Shepard, WR Darius Slayton and CB Josh Jackson
Lineup notes: WR Sterling Shepard (hamstring) and WR Darius Slayton (hamstring) are both out again. RB Saquon Barkley (knee) and WR Kenny Golladay (hip) practiced fully Friday and don’t have an injury designation.
Inactives: CB Israel Mukuamu, WR Simi Fehoko, OT Brandon Knight, S Donovan Wilson, DE Dorance Armstrong and QB Will Grier
Lineup notes: WR Michael Gallup (calf) remains on IR with a calf injury. WR Amari Cooper (hamstring) and RB Ezekiel Elliott (knee) were questionable but will start.
San Francisco 49ers at Arizona Cardinals (4:25 p.m. EST)
Kickoff Weather: 80 degrees, clear (retractable-roof dome)
Inactives: OG Aaron Banks, WR Jauan Jennings, CB Ambry Thomas, QB Jimmy Garoppolo, CB Buster Skrine, DB K’Waun Williams and NT Zach Kerr
Lineup notes: QB Jimmy Garoppolo (calf) has been ruled out and will likely miss multiple weeks. TE George Kittle (calf) was originally listed as doubtful before being put on Injured Reserve Saturday. RB Elijah Mitchell (shoulder) practiced Friday and is off the report. RB JaMycal Hasty (ankle) remains on IR.
Inactives: CB Byron Murphy, CB Marco Wilson, CB Tay Gowan, DE Victor Dimukeje, QB Chris Streveler and DL Michael Dogbe
Lineup notes: RB Chase Edmonds (shoulder) was limited all week and will give it a whirl, despite being a game-time decision.
Buffalo Bills at Kansas City Chiefs (8:20 p.m. EST)
Kickoff Weather: 73 degrees, overcast
Inactives: RB Matt Breida, OT Tommy Doyle, DT Harrison Phillips, DL Vernon Butler and LB Matt Milano
Lineup notes: No noteworthy injuries for fantasy.
Inactives: TE Noah Gray, OT Laurent Duvernay-Tardif, C Austin Blythe, WR Daurice Fountain, CB Charvarius Ward and DL Chris D. Jones
Lineup notes: WR Tyreek Hill (knee) practiced all week and is fine.
Indianapolis Colts at Baltimore Ravens (8:15 p.m. EST)
Kickoff Weather: 68 degrees, overcast
Lineup notes: QB Carson Wentz (ankles) fully practiced all week and is not on the injury report. RB Nyheim Hines (shoulder) was limited Friday but returned for a full practice Saturday and is not on the report. RT Braden Smith (foot, thumb) has been ruled out. LG Quenton Nelson (ankle) landed on IR and will miss multiple weeks.
Lineup notes: LT Ronnie Stanley (ankle) was ruled out once again. WR Rashod Bateman (groin) and WR Miles Boykin (hamstring) have not been activated from the 21-day practice window yet for Monday Night Football after being designated to return Sept. 29. (Edit: The Ravens’ official site said Saturday, 4 p.m. ET, was the deadline to play for Monday night but has since removed the reference.